A 7-Year History of Necrobiotic Xanthogranuloma following Asymptomatic Multiple Myeloma: A Case Report

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A 7-Year History of Necrobiotic Xanthogranuloma following Asymptomatic Multiple Myeloma: A Case Report

Necrobiotic xanthogranuloma (NXG) is a rare destructive xanthomatous granuloma with chronic, indolent, and progressive course. The morbidity and mortality are the results from wound complications and associated disorders. Because of its strong association with monoclonal gammopathy and multiple myeloma, early recognition of disease is mandatory to monitor and prevent systemic involvements of he...

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Necrobiotic Xanthogranuloma in a Patient with Multiple Myeloma

An 82-year-old woman presented with a 9-month history of multiple, well-defined skin lesions on her neck and upper chest, progressively increasing in size. Histological examination of a skin biopsy showed a regular epidermis. In the dermis, granulomatous changes with central necrobiosis were found which extended focally into the subcutaneous fat. The necrobiotic areas were surrounded by Touton ...

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Necrobiotic xanthogranuloma after penicillin injection: A case report

Necrobiotic xanthogranuloma (NXG) is a rare, progressive, non- Langerhans cell histiocytosis characterized by multiple yellowish indurated plaques and subcutaneous nodules that frequently involve the face, trunk, and extremities. Extracutaneous manifestations and paraproteinemia are common. Here, we report the case of a 47-year-old female who referredto the Dermatology Clinic of Razi Hospital, ...

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Periorbital necrobiotic xanthogranuloma treated successfully with novel multiple myeloma therapy.

A 46-year-old woman with a medical history of a multinodular goiter presented to the department of dermatology with extensive yellow papules and nodules surrounding both eyelids that had developed over the past 3 years. A skin biopsy was done that showed chronic granulomatous dermal inflammation and foreign body giant reaction consistent with juvenile xanthogranuloma after ruling out a ruptured...

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ژورنال

عنوان ژورنال: Dermatology Research and Practice

سال: 2011

ISSN: 1687-6105,1687-6113

DOI: 10.1155/2011/927852